Aloha Medicinals Inc. is world’s
largest and most technologically advanced producer of USDA
and EU Certified Organic medicinal mushrooms.
Aloha Medicinals Inc. is one of the
largest and most technologically advanced producers of USDA
and EU Certified Organic medicinal mushrooms and
mushroom-derived compounds in the world today. All of the
Aloha Medicinals' raw materials are produced in the United
States in Carson City, Nevada under FDA certified Good
Manufacturing Practice (cGMP) regulations, licensed by the
State of Nevada as a food manufacturing plant, fully
certified 100% Organic under USDA and EU regulations. All
Aloha Medicinals mushroom products are grown using only
Certified Organic, American produced raw materials, with
no GMO or imported ingredients used.
Aloha Medicinals Inc proprietary
solid-state fermentation process
Aloha Medicinals currently
produces more than 100 different species of mushrooms,
using a proprietary solid-state fermentation process
unlike any other. This proprietary process ensures the
maximum content of active compounds in the finished
products, guarantees absolute consistency from lot to lot,
and ensures that no heavy metals, pesticides, herbicides
or other contaminants are present in the finished
products.
Aloha Medicinals Sterility Verification
Every lot of material is
thoroughly analyzed through independent FDA certified
laboratories, ensuring quality and compliance with
strictest standards worldwide. Every lot of material we
produce is 100% guaranteed to exceed the standards set for
all microbial and quality analysis testing.
If you have special requirements we can test for any
compound you may need.
Aloha Medicinals Genetic Verification
All our mushroom strains are
genetically verified through DNA sequencing by the United
States government's National Institute of Health-National
center for Biotechnology Information {NCBI}. A copy of
this independent DNA verification is included with every
order at no cost to you, simplifying your GMP validation
process. No other manufacturer of Medicinal Mushroom
products offers this third-party genetic validation.
Aloha Medicinals Organic Verification
All products produced by
Aloha Medicinals are 100% USDA and EU Certified Organic
by Quality Assurance International –the worlds largest
and most prestigious organic certifier!
Aloha Medicinals Purity Verification
Every production lot is
independently analyzed for comprehensive panel of nearly
100 different heavy metals. Aloha Medicinals GUARANTEES
complete freedom from all contamination from heavy metals,
pesticides, herbicide and all other contaminants.
Aloha Medicinals Library of Mushroom
Cultures
Aloha Medicinals has the largest
privately owned medicinal mushroom culture bank in the
world with over 5000 different cultures. We can produce
any species of mushroom you may require.
A review on how Aloha Medicinals was able to organically cultivate the most potent Cordyceps in the world that is not only bio-identical genetically, but also bio-identical in it’s analytical signature.
Cordyceps has been used for a long time in China and Tibet. For at least a thousand years according to the written record. It was not until 1972 that the first successful Cordyceps cultivation was achieved. The first Cordyceps cultures were isolated by the Chinese Academy of Sciences in that year. These strains were not isolated from Tibet, where most of the top quality Cordyceps comes from, but rather they were isolated from specimens found in Qinghai province in Central China. Originally three different strains of Cordyceps were isolated. The first three strains, named CS-1, CS-2 and CS-3, did not have the fast growth characteristics that make commercial cultivation practical. It was the fourth culture that had been isolated by this institute, named CS-4, that was hardy and fast growing. So this CS-4 strain was chosen for commercial production.
This CS-4 culture proved itself a good candidate for commercial growth, so it was evaluated as a substitute for wild Cordyceps. It was tested for its medical potential, and by 1988 it had been approved in China as a medicine under the name Jin Shui Bao. As part of the approval process to bring this to market, many clinical and safety trials were conducted showing its efficacy and safety. That is the reason there are so many scientific articles available on this particular strain called CS-4.
But that happened a long time ago in terms of science. Think of the advances that have been made in all the sciences over the last 44 years. That is how long ago CS-4 was isolated. CS-4 is a good dietary supplement, but just because CS-4 was the first Cordyceps cultivated and studied certainly does not mean it is still the best choice today, yet many people today are taken in by the marketers that still use that early information on CS-4, telling their customers that CS-4 is the best Cordyceps for their use. This is just simply incorrect. Back in 1972 when CS-4 was isolated there was no such thing as DNA analysis. So at that time it was not realized that CS-4 contained only a part of the Cordyceps genome. CS-4 is closely related to Cordyceps sinensis, but it is not “true Cordyceps sinensis”. CS-4 is a related species called an Anamorph.
Let’s jump ahead nearly 40 years and look at where Cordyceps cultivation is today: Aloha Medicinals set out to cultivate the most potent Cordyceps back in 1999. Aloha started with the purchase of CS-4 cultures from private manufacturers in China. This was the first strain of Cordyceps Aloha produced when the company was formed on Maui in 2000. In 2001 Aloha purchased another ten Cordyceps strains from the Government of China. But Alohas research using DNA analysis and the most up-to-date analytical methods such as GC/MS and HPLC/MS showed that none of these “Cordyceps” strains were identical to wild Cordyceps. They were all related anamorphs, but they were not “True Cordyceps”.
Aloha tried every possible combination of culture techniques and growth medium, but realized that by using these part-spore cultures there was no way to gain the full potential which is known to occur in wild Cordyceps. To achieve the wild Cordyceps quality requires a much more complex approach, involving the replication of the wild Cordyceps growth conditions and triggering fusion between several part-spore cultures to achieve the full Cordyceps DNA sequence. This approach was so unique it was issued the only patent ever granted for the hybridization of mushrooms! This is the only cultivated Cordyceps available today that is genetically and analytically Bio-Identical to the wild Cordyceps occurring in Nature. This is not to be confused with Genetic Modification. Aloha Medicinals absolutely guarantees there are NO genetically modified organisms (GMO) in any Aloha Medicinals product. Aloha is opposed to the GMO approach, as well as this being forbidden under USDA and EU Certified Organic standards. Quality has no substitute. Aloha Medicinals makes the VERY BEST medicinal mushroom products in the world today
Even after Aloha had developed these bio-identical cultures though, which were 100% Cordyceps sinensis in every way, there was still a problem: The Cordyceps being grown in cultivation was still not as potent as the wild collected Cordyceps. To try and resolve this problem, Aloha Medicinals scientists undertook an expedition into the heartland of wild Cordyceps habitat, central Tibet. In May and June of 2006 Aloha Medicinals conducted one of the most comprehensive scientific research expeditions ever undertaken in the mountains of Tibet to study the natural growth parameters of wild Cordyceps. Working with the local nomad people, Aloha identified several hundred Cordyceps specimens growing directly from the ground. Aloha carefully measured all the growth conditions there, such as pH, soil and air temperature and composition, moisture content in the air and soil, the other micro-organisms found in the area, air pressure and virtually everything else that could be measured, Aloha did.
Aloha brought this information back to the lab, and developed entirely new methods of cultivation, which have resulted in Cordyceps that is not only bio-identical genetically, but also bio-identical in it’s analytical signature. Bringing the latest of 21st century American biotechnology to this field has resulted in a quantum leap in Cordyceps cultivation, reducing the cost and increasing the quality of cultivated Cordyceps. These cultivation methods involved building special growing chambers where the oxygen is held at 50% of the normal atmospheric oxygen, and the temperature is held at just above freezing. This exactly replicates the conditions found during the growing season in Nepal and Tibet at 18,000 feet (5400 meters) elevation. This Low Temperature, Low Oxygen growth is also patented. Aloha Medicinals is the only company in the world that grows Cordyceps using these techniques.
Aloha Medicinals' Quality Control and
third-party DNA certification
Aloha Medicinals' Quality Control
is the best in the industry. All mushroom species grown
are third-party DNA certified through the U.S. National
Institute of Health – National Center for Biotechnology
Genebank (NCBI), and all required chemical and microbial
assays are performed by independent FDA certified,
third-party analytical laboratories. A Certificate of
Analysis and a full chemical and DNA profile is provided
with each lot. While most manufacturers test only for the
few items required by FDA such as the total plate count
and e-coli content, at Aloha Medicinals we analyze for a
comprehensive array of substances. This includes more than
90 heavy metals, full polysaccharide profile including
beta glucans, heteropolysaccharides and residual starches,
all microbial and sterility tests, plus any specialized
analysis that may be required by the client.
Aloha Medicinals - “Exporter of the
Year Award” honored by the U.S. Department of Commerce
Due to this state-of-the-art
manufacturing and unexcelled quality control program,
Aloha was proud to accept the U.S. Department of Commerce
“Exporter of the Year Award” for its top quality exports
in the field of pharmaceutical and supplement raw
materials. Aloha currently supplies over 700 companies in
more than 60 countries with raw materials for their
branded products.
Aloha
Medicinals guarantee there are no other Medicinal
Mushroom products available anywhere in the world
today with more potency or consistency or a higher
quality than the raw materials produced by Aloha
Medicinals Inc.
Here is a list of some of our more
popular strains available for custom formulation:
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Aloha
Medicinals Agaricus Blazei Full
Spectrum
- Now Available in Nano Formulation!
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Certificate
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Aloha
Medicinals Full Spectrum Chaga
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Certificate
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Aloha
Medicinals GanoUltra™ Full Spectrum
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Aloha
Medicinals GanoSuper™ Concentrated 4:1 purified
and micronized extract.
Special Low Taste/Low Odor extract ideal for
drink application
or high potency supplements USDA and EU
Certified Organic
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Certificate
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Aloha
Medicinals Red Reishi™ Full
Spectrum MycoProduct
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Certificate
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Aloha
Medicinals Grifola frondosa Full
Spectrum
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Certificate
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Aloha
Medicinals Hericium Erinaceus Full
Spectrum
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Certificate
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Aloha
Medicinals Lentinula edodes Full
Spectrum
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Certificate
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Aloha
Medicinals Cordyceps is the only Bio-Identical
Cordyceps
grown in patented low oxygen, low temperature
conditions,
just like nature!
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Aloha
Medicinals Pure Cordyceps Super™ Full Spectrum
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Corioulus
Versicolor Full Spectrum
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Immune Assist 24/7™ is a completely unique combination of over 200 different hetero-polysaccharides, derived from the enzymatic breakdown of complex organic plant material from five different species of medicinal mushrooms.
- These includes USDA and EU Organic Certified Extracts of:
Agaricus blazei,
Cordyceps sinensis,
Lentinula edodes (shiitake),
Grifola frondosa (maitake),
Ganoderma lucidum (Reishi) including
Epigallocatechin gallate, “ECGC”, also known as epigallocatechin-3-gallate, tea catechin.
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Immune Assist Critical Care Formula ™ is a combination of over 200 highly purified, immune-active High Molecular Weight (HMW) Hetero- polysaccharides and Beta 1,3-1,6 triple right hand helix Beta Glucans.
- The five most potent immune supporting species of mushrooms used are: USDA and EU Organic Certified Extracts of:
Agaricus blazei,
Cordyceps sinensis,
Lentinula edodes (shiitake),
Grifola frondosa (maitake) and
Ganoderma lucidum (Reishi).
- These immune-active heteropolysaccharides and Beta Glucans are concentrated by more than 250 to 1 ratio and then purified into a pharmaceutical grade immune enhancing ingredient.
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Aloha Medicinals Agaricus Bisporus as Full
Spectrum MycoProduct™
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Aloha Medicinals Auricularia Auricula Full Spectrum
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Aloha Medicinals Coprinus Comatus Full Spectrum
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Performax Forte™ is a cutting-edge herbal and mushroom formulation that provides a healthy way to help promote and support your energy levels throughout the day.
- Whether you are chasing the gold medal or chasing your two-year-old, Performax Forte™ is the all-natural way to increase energy and performance.
- Consisting of the finest blend of Rhodiola rosea and Pure Cordyceps™, with Magnesium and Chromium for increased potency, this product is the best supplement for increased performance available today.
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The Aloha Medicinals Advantage
Full Spectrum Mycoproducts™
There is a lot of confusion today
from all the marketing claims on the internet about what
form of mushroom product is the best to use. Some say it
is the fruitbody, or the mycelium, or a hot water extract
standardized for some particular compound. This is an
important question and the answer should be based in
scientific fact, not on historical usage or on someone's
opinion. There is a lot of amazingly complex bio-chemistry
going on in the mushroom kingdom which can be valuable for
its health giving potential. We have accurately addressed
this issue here so you can decide which health supplement
raw materials are the best for your use or for use in your
product formulation.
Let's start with some Definitions
Fruitbody
‘Fruitbodies’ are the mushrooms you see growing out of the
ground or from that old dead tree. They are the
reproductive part of the organism, like the flower of a
plant. Just like flowers will only bloom during a certain
season, Fruitbodies will only form in response to some
stress in the environment, such as heat, or cold, fire or
flood, running out of food, or some other stress that
forces the organism into a “reproduce or die” mode. The
mushroom fruitbodies that you see are NOT the growth form
of the mushroom organism. It is strictly the reproductive
part of the fungus at the end of its life cycle.
Mycelium
‘Mycelium’ is the growth form of the organism. This is the
state in which all of the life processes occur, such as
growth, feeding and competing for survival (including
antibiotic, antifungal and antiviral compound production).
In cultivated mushroom products, the mycelium can be grown
by fermentation in a tank full of liquid as beer and wine
are “grown”. This is a highly unnatural growth condition,
and mushrooms grown this way do not have the same chemical
profiles as those that are grown naturally. Another way
that medicinal mushroom mycelium can be grown is on a
solid substrate of some material that it would normally
grow on – which is the natural growth condition. For
production of most mushroom-derived drugs, the compounds
are extracted not from the mycelium, but are actually
extracted from the broth or substrate the mycelium is
grown in.
Extracts
‘Extract’ is a word that covers a lot of possibilities.
Extracts are usually made from either mushrooms or
mycelium, which are extracted with some type of solvent
with the intention of concentrating some desirable portion
and eliminating or reducing some non-desirable portion of
the fungus. There are a number of solvents which are used,
depending on which type of compounds the extractor is
hoping to concentrate. The two most common solvents used
are Alcohol and Water. Extracts tend to be more expensive
than raw materials and they may be either more potent or
less potent than the raw material, depending upon which
compounds are being concentrated and the desired end use
of the material. The widely held belief that extracts are
somehow “more potent” than other forms of mushroom
material is too simplified to be true, and is simply
incorrect. But this thinking is the result of historical
usage and dubious internet marketing claims, as you will
read below. The following section should make it clear so
you will understand how extracts are made, what their uses
are, and why there is so much misunderstanding about them.
Full
Spectrum
‘Full Spectrum Myco-Products’ are the complete fungal
material consisting of all the biologically active
components, such as the mycelium, the fruitbodies
and by far the most important of all, the
extra-cellular compounds that are produced throughout the
entire life cycle of the organism. It is these
extra-cellular compounds (compounds that are excreted
outside of the cell and into the surrounding environment)
that are responsible for the main medicinal properties
known from the fungal kingdom, such as all the antibiotic
properties, antiviral properties, antifungal properties
and all the other ‘survival’ compounds that the fungus
produces to give itself an advantage over the competing
bacteria and microbes in the highly competitive
environment in which it lives. These secondary metabolites
have opened up the frontiers of medicine, with such
breakthroughs as antibiotics and cholesterol lowering
drugs. And it is these properties that are removed through
most extraction processes. It is only in the 21st century
that science has developed practical ways to reliably
produce full spectrum myco-products which are now
considered the current “Gold Standard” for most mushroom
based dietary supplements.
Basis for Quality Determination in
Medicinal Mushrooms
History
While medicinally active mushrooms have certainly been
collected from nature and used for a long time, the
cultivation of mushrooms specifically for the production
of medicinal compounds is a new science, dating only from
the late 1970's. Since that time there have been a number
of bio-active ‘compounds of interest’ identified from
mushrooms including different compounds from the
fruitbodies, from the mycelium and from the residual
culture broth or solid substrate residue. In almost every
case, the main cellular components found in the different
life stages are identical. But there are differences in
the ‘secondary metabolites’ produced, where substantially
greater amounts of particular compounds can be extracted
from one growth stage as compared to some other growth
stage. Many examples of this can be seen in the scientific
article authored by Dr. Solomon Wasser: Medicinal
Properties of substances occurring in Higher
Basidiomycetes Mushrooms: Current Perspectives
(Review) [pdf] published in - International
Journal of Medicinal Mushrooms.
What is the most practical way to produce medicinal
mushroom products with the greatest effectiveness, while
keeping them affordable enough for the general public?
Even just ten years ago this was a problem because solid
state fermentation had not yet been perfected, and growing
mushrooms in liquid culture as with beer or wine requires
extraction of the compounds left behind in the broth in
order to capture all the health properties. This
processing step raises the cost beyond what is practical
for most people to spend on their dietary supplements. It
is easy for a company to purchase wild collected
mushrooms, or to grow mushroom fruitbodies on a farm and
then extract them for supplement uses. To produce
medicinal mushroom products with low potency is
counterproductive, since they will not have a large
consumer following if they do not work. So most companies
take the easy approach of growing or buying mushroom
fruitbodies, and then making a tea which is spray dried
and called a “hot water extract”. Many claim this is the
best form to use, or even that it is the only bioactive
way to use mushrooms, which is of course nonsense, since
mushrooms have been eaten for their health properties for
thousands of years. The concept that extracts are
better than anything else is yesterday’s science and it
does not reflect today’s state-of-the-art knowledge.
These “hot water extracts” are certainly better than
trying to digest hard woody fruitbodies such as Reishi,
but this extraction process entirely misses the
potential health benefits which are offered by the
extra-cellular compounds, which are not present in the
fruitbodies. Some other companies will just
grow the mycelium. This can be a better choice than
fruitbodies if grown in solid substrate, but the mycelial
products can be a problem if they are not produced
according to strict FDA certified Good Manufacturing
Practice (cGMP) biotechnology sterile tissue culture
standards, and some mycelium products often contain up to
70% of unconverted substrate, like rice or wheat. All
Aloha Medicinals products are guaranteed to contain less
than 2% of residual substrate material in the finished
product.
In developing our production
processes, Aloha Medicinals looked long and hard at the
chemistry of the wild collected fruitbodies, of the
mycelia and of the extra-cellular compounds, and all that
was known about the bioactivity of each in the human body.
We then developed special growing methods including custom
made growing chambers, strictly defined growth substrates
(no sawdust, straw or compost is used) and specially
modified growth parameters such as full year-round climate
control for temperature, light cycle, and air quality and
composition to maximize the production of the targeted
medicinal compounds. By controlling each and
every aspect of the growth cycle, Aloha Medicinals is
able to produce the best quality, the most potent and
the most consistent medicinal mushroom products
available anywhere in the world today, while ensuring
against all possible contamination of heavy metals,
pesticides, herbicides or insect residue as is so common
in other mushroom products.
One great advance Aloha Medicinals
made to the science of mushroom growing is our
patent-pending proprietary methods for growing mushrooms
in glass and plastic containers for a long enough period
of time to completely bio-convert all of the raw substrate
material into fungal tissue and extra-cellular compounds.
By the time of harvest we have obtained all of the
different health giving aspects that the mushroom present.
This long growth period takes at least several months, and
for some species it can take up to two years. When
a supplier promises they can deliver a finished, custom
grown product in 30 to 45 days, you can be certain that
the quality will be very low. In nature it takes from
months-to-years for a mushroom colony to become
established. That is why you find mushrooms
growing in the same place year after year. They produce
mushrooms every spring just like a tree produces flowers,
but the mushroom organism itself exists from year to year
in the soil below. To think that we can trick that
organism into optimal growth in the lab in just a few
weeks is wishful thinking indeed. But this is what many
mushroom cultivators claim to do.
For some species, Aloha Medicinals
has resorted to extreme culture parameters; for example we
grow out our Cordyceps sinensis for a period of time in a
warm, oxygen rich environment, after which we drastically
lower the temperature to just above freezing, we change
the light cycle and we drop the oxygen to no more than 50%
of the normal atmospheric content. All of this is done on
an organic, vegetarian substrate with no insect or animal
substances used. While this may seem extreme compared to
how other cultivators grow their medicinal mushroom
products, Aloha Medicinals is proud to point out
the products we make are the best quality, highest
potency medicinal mushroom products in the world. This
is proven by the phenomenal growth Aloha Medicinals has
experienced over the last 10 years, making us the
largest cultivators of exclusively Certified Organic
Medicinal Mushrooms today with a monthly production
capacity of nearly 200 tons of finished products per
month. We currently supply over 700 companies
with the raw material used in their formulations, and in
2009 we exported to 56 countries, which won us the U.S.
Department of Commerce “Exporter of the Year” Award, the
second year in a row we were awarded special recognition
for our quality products.
If you want the best medicinal
mushroom products available today, Aloha Medicinals is
your best choice. 100% Certified Organic by USDA
and EU, 100% Certified Kosher by Star K, and 100%
Guaranteed. It does not get any better than
this. Certified Organic and 100% made in America with
all-American ingredients. Why risk the reputation of your
products on imported raw materials, when the best quality
is available right here in America, using state of the art
science and Independently Assayed by FDA certified labs
for DNA and Analytical profile. All this is available at a
price lower than imported raw materials in most cases.
Whether you need Full Spectrum Myco-products, or a
concentrated extract, or even research grade materials, we
supply it all. Let us bid your next order for medicinal
mushroom raw materials. You will be pleasantly surprised!